Fentanyl Addiction

Fentanyl addiction is caused by long term intake of the very potent prescription pain medication under the brand names Duragesic® and Ionsys®.

• Duragesic 25 micrograms (mcg) per hour
• Duragesic 50 mcg per hour
• Duragesic 75 mcg per hour
• Duragesic 100 mcg per hour
• Ionsys 40 mcg per activation

Other brand or generic formulations may also be available.

DURAGESIC® contains a high concentration of a potent Schedule II opioid agonist, fentanyl. Schedule II opioid substances which include fentanyl, hydromorphone, methadone, morphine, oxycodone, and oxymorphone have the highest potential for abuse and associated risk of fatal overdose due to respiratory depression. The high content of fentanyl in the patches (DURAGESIC®) may be a particular target for abuse and diversion.The concomitant use of DURAGESIC® with potent cytochrome P450 3A4 inhibitors (ritonavir, ketoconazole, itraconazole, troleandomycin, clarithromycin, nelfinavir, and nefazodone) may result in an increase in fentanyl plasma concentrations, which could increase or prolong adverse drug effects and may cause potentially fatal respiratory depression.

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